Summary statistics from the fitted model and comparisons between chronic cough patients and healthy volunteers are presented below as adjusted geometric means and the pairwise differences ratios of the adjusted means
| C5 Capsaicin Concentration – Adjusted Means and Difference Ratios between Subject Types | ||||||
| Chronic Cough Patients (N = 10) | Healthy Volunteers (N = 12) | Chronic Cough Patients vs. Healthy Volunteers | ||||
| Adjusted Geometric Mean (μM) | Adjusted Geometric Mean (μM) | Geometric Mean Ratio with 95% CI | pairwise p-value | |||
| Overall | 35.2 | 77.4 | 0.46 | 0.20, 1.09 | 0.078 | |
| By Infusion Type | ||||||
| Acid | 29.5 | 83.8 | 0.36 | 0.15, 0.88 | 0.025 | |
| Saline | 41.8 | 71.4 | 0.42 | 0.20, 0.87 | 0.019 | |
| By Infusion Type and Order | ||||||
| Acid | ||||||
| Acid-Saline | 20.0 | 114.3 | - | - | - | |
| Saline-Acid | 43.5 | 61.3 | - | - | - | |
| p-value | 0.039 | 0.367 | - | - | - | |
| Saline | ||||||
| Acid-Saline | 30.8 | 105.4 | - | - | - | |
| Saline-Acid | 56.7 | 48.3 | - | - | - | |
| p-value | 0.245 | 0.167 | - | - | - | |
#Ratio <1: Chronic Cough Patients required lower concentrations than Healthy Volunteers.
Ratio >1: Chronic Cough Patients required higher concentrations than Healthy Volunteers