Study groups and outcome measures
| Control (n = 12) | VC (n = 9) | TH (n = 9) | |
| Sex (M/F) | 7/5 | 4/5 | 7/2 |
| Mean (SD) age, years | 9.0 (2.0) | 9.9 (3.3) | 9.9 (1.3) |
| Mean (SD) FEV1% predicted at visit 1 | 84.2 (19.6) | 84.1 (13.9) | 91.2 (14.6) |
| Median (quartiles) incorrect MDI steps at visit 1 | 2.0 (0; 4.75) | 10 (6.5; 10) | 6 (5; 9) |
| Median (quartiles) incorrect MDI steps at visit 2 | 0.5 (0; 2.75) | 1.0 (0; 2.0) | 0.0 (0; 0.5) |
| Mean (SD) peak IF pre-training at visit 1, l/min | 46.7 (8.2) | 99.1 (55.4) | 115.8 (24.1) |
| Mean (SD) peak IF at visit 2, l/min | 75.0 (34.2) | 98.9 (65.8) | 66.1 (19.0) |
| Mean (SD) ACQ at visit 1 | 1.14 (0.59) | 2.43 (1.85) | 2.39 (1.10) |
| Mean (SD) ACQ at visit 2 | 0.74 (0.93) | 0.82 (0.64) | 0.70 (0.97) |