Table 3

Likelihood of still being alive 2 years after diagnosis, by SEP, adjusted for selected patient, tumour and system factors, for those with stage recorded

Variable	Adjusted—IMD, age, sex, histology, year, CCI, timely GP referral (n=5233, R²=3.72)				Adjusted—IMD, age, sex, histology, year, CCI, timely GP referral, stage, PS (n=5233, R²=26.59)				Adjusted—IMD, age, sex, histology, year, CCI, timely GP referral, stage, PS, treatment (n=5233, R²=31.73)				Adjusted—IMD, age, sex, histology, year, CCI, timely GP referral, stage, PS, treatment, timely 1st treatment (n=5233, R²=32.04)
Variable	OR	95% CI		p Value	OR	95% CI		p Value	OR	95% CI		p Value	OR	95% CI		p Value
Deprivation quintile				0.017				0.221				0.761				0.800
1 (least deprived)	1.00				1.00				1.00				1.00
2	0.92	0.71	1.20	0.544	0.97	0.72	1.31	0.834	1.02	0.74	1.40	0.923	1.01	0.73	1.39	0.966
3	0.92	0.72	1.19	0.534	1.00	0.75	1.34	0.993	1.08	0.79	1.47	0.641	1.07	0.78	1.46	0.672
4	0.72	0.56	0.91	0.007	0.77	0.58	1.02	0.064	0.90	0.67	1.21	0.505	0.91	0.67	1.22	0.511
5 (most deprived)	0.76	0.61	0.96	0.019	0.90	0.70	1.17	0.452	1.03	0.78	1.36	0.849	1.02	0.77	1.34	0.900
Age group (years)				<0.001				<0.001				0.687				0.668
<60	1.00				1.00				1.00				1.00
60–69	1.06	0.86	1.31	0.601	1.03	0.81	1.32	0.793	1.12	0.86	1.45	0.411	1.11	0.85	1.44	0.452
70–79	0.79	0.64	0.97	0.026	0.75	0.59	0.96	0.024	1.03	0.78	1.34	0.853	1.00	0.77	1.31	0.989
80+	0.53	0.41	0.68	<0.001	0.49	0.36	0.67	<0.001	0.95	0.68	1.33	0.786	0.94	0.67	1.31	0.712
Sex				<0.001				<0.001				<0.001				<0.001
Female	1.00				1.00				1.00				1.00
Male	0.75	0.65	0.86	<0.001	0.70	0.59	0.82	<0.001	0.69	0.58	0.82	<0.001	0.69	0.58	0.82	<0.001
Histology				<0.001				<0.001				0.0005				0.007
NSCLC	1.00				1.00				1.00				1.00
SCLC	0.32	0.22	0.47	<0.001	0.49	0.32	0.76	0.001	0.48	0.31	0.74	0.001	0.55	0.35	0.85	0.008
Other	0.65	0.54	0.78	<0.001	0.80	0.64	1.00	0.047	1.19	0.93	1.52	0.176	1.18	0.92	1.51	0.190
Year of diagnosis				0.698				0.931				0.431				0.411
2006	1.00				1.00				1.00				1.00
2007	1.03	0.80	1.33	0.831	1.07	0.80	1.43	0.660	1.02	0.75	1.38	0.910	1.00	0.73	1.36	0.993
2008	0.91	0.72	1.15	0.423	1.09	0.83	1.44	0.523	1.02	0.77	1.37	0.868	0.98	0.74	1.31	0.918
2009	0.95	0.72	1.25	0.704	1.09	0.79	1.50	0.594	0.82	0.59	1.14	0.242	0.79	0.57	1.11	0.175
Comorbidity score				0.071				0.218				0.025				0.021
0	1.00				1.00				1.00				1.00
1–2	1.22	0.95	1.58	0.123	1.21	0.90	1.64	0.202	1.35	0.99	1.84	0.060	1.35	0.99	1.84	0.060
3+	1.00	0.63	1.58	0.998	0.83	0.49	1.40	0.479	1.06	0.61	1.83	0.843	1.02	0.59	1.78	0.934
Missing	0.85	0.68	1.07	0.168	0.93	0.71	1.21	0.575	0.90	0.68	1.18	0.455	0.90	0.68	1.18	0.434
Unavailable	1.05	0.83	1.34	0.663	1.19	0.91	1.58	0.209	1.40	1.04	1.88	0.025	1.40	1.05	1.89	0.024
Timely GP referral				<0.001				<0.001				0.137				0.165
No GP referral date	1.00				1.00				1.00				1.00
FHA≤14 days	1.44	1.22	1.70	<0.001	1.36	1.12	1.66	0.002	1.23	1.00	1.52	0.048	1.22	0.99	1.50	0.059
FHA>14 days	1.87	1.52	2.30	<0.001	1.33	1.05	1.70	0.019	1.16	0.90	1.50	0.252	1.15	0.89	1.48	0.288
Stage								<0.001				<0.001				<0.001
I					1.00				1.00				1.00
II					0.40	0.30	0.53	<0.001	0.47	0.34	0.63	<0.001	0.47	0.35	0.64	<0.001
III					0.14	0.12	0.17	<0.001	0.23	0.18	0.29	<0.001	0.24	0.19	0.30	<0.001
IV					0.04	0.04	0.06	<0.001	0.09	0.07	0.12	<0.001	0.10	0.07	0.13	<0.001
Performance status								<0.001				<0.001				<0.001
0					1.00				1.00				1.00
1–2					0.53	0.44	0.64	<0.001	0.75	0.61	0.92	0.007	0.76	0.62	0.94	0.011
3–4					0.18	0.13	0.25	<0.001	0.44	0.30	0.65	<0.001	0.46	0.31	0.67	<0.001
Missing					0.47	0.35	0.64	<0.001	0.70	0.51	0.97	0.034	0.72	0.52	0.99	0.045
Type of treatment												<0.001				<0.001
No treatment									1.00				1.00
Surgery									11.24	7.78	16.24	<0.001	12.86	8.84	18.70	<0.001
Surgery + chemotherapy and/or radiotherapy									13.13	8.78	19.63	<0.001	14.94	9.93	22.49	<0.001
Chemotherapy									2.48	1.70	3.62	<0.001	2.81	1.92	4.11	<0.001
Chemotherapy + radiotherapy									4.75	3.41	6.61	<0.001	5.43	3.87	7.60	<0.001
Radio									2.24	1.67	3.00	<0.001	2.47	1.83	3.32	<0.001
Timely 1st treatment																<0.001
>31 days from diagnosis													1.00
<31 days from diagnosis													0.63	0.51	0.79	<0.001

CCI score, Charlson Comorbidity Score; FHA, first hospital appointment; IMD, Index of Multiple Deprivation; NSCLC, non-small cell lung cancer; SCLC, small cell lung cancer.