Mean difference in FVC between treatment groups for the intention-to-treat (ITT, n=46), ‘as treated’ (n=46) and Completer (n=33) populations
| Outcome FVC (L) | Mean difference in FVC (azithromycin minus placebo) | 95% CI for population mean difference | p Value |
|---|---|---|---|
| ITT analysis 46 patients, 177 measurements | |||
| Mean difference in FVC between treatment arms, adjusted for baseline FVC, randomisation stratification variables (disease and transplant) and time since randomisation | 0.099 | −0.026 to 0.224 | 0.1 |
| ‘As treated’ analysis 46 patients, 177 measurements | |||
| Mean difference in FVC between treatment arms, adjusted for baseline FVC, randomisation stratification variables (disease and transplant) and time since randomisation | 0.272 | 0.158 to 0.386 | <0.001 |
| Completers analysis 33 patients, 124 measurements | |||
| Mean difference in FVC between treatment arms, adjusted for baseline FVC, randomisation stratification variables (disease and transplant) and time since randomisation | 0.248 | 0.115 to 0.381 | <0.001 |