Table 4

Pulmonary function results at initial and follow-up assessment

2003–20052009–2010p Value
FEV180.6 (41.9–115.4)70.9 (25.5–98.4)0.0004
VC80.5 (48.4–102.3)74.5 (27.1–106.6)0.0347
FEV1:VC104.8 (90.9–129.3)98.7 (74.0–113.0)0.0261
FEF25/7587.0 (33.5–136.3)70.1 (19.6–129.2)0.0033
TLC87.6 (67.2–107.0)85.5 (63.8–109.6)0.5628
RV87.6 (46.3–125.0)90.0 (50.1–162.6)0.1213
RV:TLC102.0 (56.1–160.4)111.1 (64.6–197.0)0.0383
DLCOc74.1 (42.7–104.1)74.3 (45.3–104.8)0.9879
KCOc111.5 (85.0–154.9)104.8 (77.0–137.8)0.0325
SpO2(%)*97 (84–99)97 (85–100)0.4380
  • *Data are expressed as median (range) and presented as per cent predicted for height, age and sex unless indicated.

  • RV:TLC, residual volume:total lung capacity ratio; VC, vital capacity.