Healthy | COPD | |||||||
---|---|---|---|---|---|---|---|---|
OS | HP | Δd | p | OS | HP | Δd | p | |
Spirometry (difference%) | ||||||||
FEV1 1 h | 0.78 | 3.46 | -2.68 | 0.09 | -2.30 | 1.70 | -4.00 | 0.01 * |
FEV1 2 h | 0.49 | 2.38 | -1.89 | 0.17 | -1.43 | -0.38 | -1.05 | 0.39 |
FEV1 6 h | 1.84 | 7.89 | -6.05 | 0.01 * | 1.68 | 2.08 | -0.41 | 0.79 |
FEV1 24h | 0.05 | 4.22 | -4.17 | 0.01 * | 1.85 | 0.92 | 0.93 | 0.65 |
FVC 1 h | 0.00 | 1.81 | -1.81 | 0.28 | -1.84 | 1.57 | -3.41 | 0.02 * |
FVC 2 h | -1.00 | 1.16 | -2.16 | 0.32 | -3.22 | -0.11 | -3.11 | 0.09 |
FVC 6 h | 0.22 | 3.57 | -3.35 | 0.17 | 1.38 | 1.60 | -0.22 | 0.90 |
FVC 24h | -1.60 | -2.84 | 1.24 | 0.68 | 1.60 | 2.54 | -0.95 | 0.73 |
IOS 5hz (difference kPa/l/s) | ||||||||
IOS 5hz 4 h | -0.01 | -0.01 | 0.00 | 0.78 | 0.03 | -0.02 | 0.05 | 0.01 * |
IOS 20hz 4 h | -0.01 | -0.02 | 0.01 | 0.48 | -0.01 | -0.04 | 0.03 | 0.09 |
IOS 20hz (difference kPa/l/s) | ||||||||
IOS 20hz 4 h | -0.01 | -0.01 | 0.00 | 0.80 | -0.72 | -0.03 | -0.68 | 0.35 |
IOS 20hz 24h | -0.01 | -0.01 | 0.00 | 0.73 | 0.00 | -0.03 | 0.02 | 0.04 * |
FeNO (difference ppb) | ||||||||
3h | -5 | -4 | -1 | 0.75 | -2 | -4 | 2 | 0.71 |
5h | -4 | -2 | -2 | 0.37 | -7 | -7 | -1 | 0.89 |
24h | -4 | -1 | -3 | 0.26 | 2 | -6 | 8 | 0.09 |
PWV (difference m/s) | ||||||||
3 h | -0.1 | -0.2 | 0.2 | 0.47 | 0.1 | -0.6 | 0.8 | 0.03 * |
6h | 0.3 | 0.0 | 0.3 | 0.32 | 0.2 | -0.3 | 0.5 | 0.03 * |
24 h | 0.6 | -0.4 | 1.0 | 0.04 * | 0.3 | -0.4 | 0.7 | 0.32 |
* p < 0.05
Δ d Mean difference of difference between each exposure site