Comparison between frail and non-frail patients with COPD
| Frail (n = 446) | Non-Frail (n = 54) | p value | |
|---|---|---|---|
| Age (years) | 66 (7) | 65 (7) | 0.380 |
| FEV1% predicted | 58 (20) | 66 (21) | 0.011 |
| BMI (kg/m2) | 28.2 (5.6) | 26.4 (3.2) | 0.049 |
| Waist circumference (cm) | 100 (15) | 94 (10) | 0.025 |
| Fat Mass (kg) | 27.1 (11) | 23.1 (7.2) | 0.027 |
| HGS (kg) | 26.6 (9.7) | 32.5 (10.1) | 0.001 |
| Aortic PWV (m/s) | 10.0 (2.4) | 9.0 (1.9) | 0.012 |
| Stroke Volume (ml) | 85 (20) | 92 (23) | 0.042 |
| Central systolic blood pressure | 146 (19) | 143 (16) | 0.377 |
| Central diastolic blood pressure | 84 (11) | 82 (9) | 0.643 |
| Central mean blood pressure | 104 (12) | 103 (11) | 0.605 |
| 6MWD (m) | 313 (121) | 450 (72) | 0.001 |
| TUG (s) | 11.3 (3.8) | 8.7 (1.4) | 0.001 |
| Smoking (packs/year) | 41 (25) | 36 (23) | 0.229 |
| No. Exacerbations/ year | 2.3 (1) | 1.0 (1) | 0.001 |
| CRP (mg/L)# | 3.6 (2.9) | 2.80 (2.2) | 0.174 |
| SGRQ | 53.1 (19.1) | 21.6 (13.6) | 0.001 |