Putative risk factors for pneumococcal CAP following univariate analysis
| Pneumococcal CAP (n=410) | Non-pneumococcal CAP (n=720) | OR | 95% CI | p Value | |
|---|---|---|---|---|---|
| Age* | 70.0 (50.0–80.1) | 71.6 (59.0–80.3) | 0.091 | ||
| Male sex | 217 (52.9) | 434 (60.3) | 0.72 | 0.56 to 0.92 | 0.008 |
| Positive smoking history | 289 (70.5) | 481 (66.8) | 1.14 | 0.88 to 1.49 | 0.324 |
| PPV | 160 (39.0) | 307 (42.6) | 0.90 | 0.69 to 1.16 | 0.410 |
| Malignancy | 21 (5.1) | 61 (8.4) | 0.58 | 0.34 to 0.96 | 0.032 |
| Liver disease | 8 (2.0) | 5 (0.69) | 2.81 | 0.91 to 8.65 | 0.060 |
| CCF | 28 (6.8) | 52 (7.2) | 0.93 | 0.58 to 1.50 | 0.773 |
| Stroke disease | 48 (11.7) | 75 (10.4) | 1.12 | 0.76 to 1.65 | 0.550 |
| Chronic kidney disease | 29 (7.1) | 44 (6.1) | 1.16 | 0.71 to 1.88 | 0.553 |
| Asthma | 54 (13.1) | 67 (9.3) | 1.46 | 1.00 to 2.13 | 0.050 |
| COPD | 62 (15.1) | 129 (17.9) | 0.80 | 0.58 to 1.12 | 0.195 |
| Diabetes | 53 (12.9) | 104 (14.4) | 0.87 | 0.61 to 1.24 | 0.429 |
| Dementia | 18 (4.4) | 20 (2.8) | 1.59 | 0.83 to 3.03 | 0.160 |
| HIV | 2 (0.5) | 3 (0.4) | 1.16 | 0.19 to 6.95 | 0.873 |
| Child contact | 148 (36.1) | 181 (25.1) | 1.68 | 1.29 to 2.18 | <0.001 |
Bold values represent p values reaching statistical significance (<0.05).
All values given as n (%) unless stated otherwise.
*Median years (IQR).
CAP, community acquired pneumonia; CCF, congestive cardiac failure; COPD, chronic obstructive pulmonary disease; PPV, pneumococcal polysaccharide vaccination.