CO-validated 4-week abstinence* | ||
OR (95% CI) | p Value | |
Medication | ||
Single NRT vs no medication | 1.75 (1.39 to 2.22) | <0.001 |
Combination NRT vs single NRT | 1.42 (1.06 to 1.91) | 0.019 |
Bupropion (Zyban) vs single NRT | 1.12 (0.96 to 1.30) | 0.160 |
Varenicline (Champix) vs single NRT | 1.78 (1.57 to 2.02) | <0.001 |
Intervention type (reference: one-to-one) | ||
Closed group | 1.43 (1.16 to 1.76) | 0.001 |
Drop-in | 0.72 (0.57 to 0.90) | 0.003 |
Open (rolling) group | 1.46 (1.19 to 1.78) | <0.001 |
Telephone support† | – | – |
Other | 0.97 (0.68 to 1.38) | 0.851 |
Intervention setting (reference: specialist clinics) | ||
Primary care | 0.80 (0.66 to 0.99) | 0.037 |
Pharmacy | 0.94 (0.83 to 1.06) | 0.303 |
Other | 0.87 (0.69 to 1.10) | 0.239 |
Treatment episode (later vs first) | 0.99 (0.90 to 1.08) | 0.749 |
* Adjusted for gender (reference: male; OR 0.93, 95% CI 0.90 to 0.96, p<0.001), age (per year increase: OR 1.02, 95% CI 1.01 to 1.02, p<0.001), ethnicity (reference: white; NS), occupation (reference: routine and manual; sick/disabled and unable to work: OR 0.62, 95% CI 0.57 to 0.67, p<0.001; never worked/long-term unemployed: OR 0.68, 95% CI 0.63 to 0.74, p<0.001; full-time student: OR 0.72, 95% CI 0.64 to 0.81, p<0.001; home carer: NS; retired: NS; intermediate: OR 1.15, 95% CI 1.03 to 1.28, p=0.011; managerial/professional: NS; in prison: NS) and prescription charges (reference: exemption; not exempt: OR 1.15, 95% CI 1.10 to 1.21, p<0.001).
† Due to the nature of a telephone intervention, CO validation was not attempted in most cases so this result would not be reliable and is not presented.
Strata=1, cluster=24, sampling design df=23.
CO, carbon monoxide; NRT, nicotine replacement therapy; SSS, stop smoking service.