Estimates for the interaction between gas cooking and genetic variants in GSTM1, GSTT1 and GSTP1 on bronchial responsiveness in the European Community Respiratory Health Survey II
| Genetic variant | Whole sample | ‘Random’ sample | ‘Enriched’ sample* | ||||||
|---|---|---|---|---|---|---|---|---|---|
| N | β (95% CI) | p Value | N | β (95% CI) | p Value | N | β (95% CI) | p Value | |
| GSTM1 null | 2208 | −0.75 (−1.16 to −0.33) | 4×10−4 | 1843 | −0.81 (−1.34 to −0.28) | 0.003 | 365 | −0.93 (−2.01 to 0.14) | 0.088 |
| GSTT1 null | 2208 | −0.02 (−0.54 to 0.50) | 0.929 | 1843 | −0.27 (−0.83 to 0.28) | 0.336 | 365 | 0.74 (−0.57 to 2.04) | 0.270 |
| GSTP1-rs1695 | 2444 | 0.03 (−0.41 to 0.46) | 0.905 | 2018 | 0.01 (−0.45 to 0.48) | 0.954 | 426 | 0.31 (−0.48 to 1.11) | 0.441 |
*France and Switzerland were considered as one group due to small numbers in those two countries.