Incidence of pleural mesothelioma adjusted for sex, time since first exposurea, time since first exposureb duration of exposurea, source of asbestos exposure and crocidolite (707 cases and up to 150 controls per case (min 29:max 150)) and incidence of peritoneal mesothelioma adjusted for sex, time since first exposureb, duration of exposureb and source of asbestos exposure (155 cases and up to 150 controls per case (min 66:max 150))
| Variables | Coef. | 95% CI | p Value |
|---|---|---|---|
| Pleural mesothelioma | |||
| Sex | −0.41 | −0.63 to 0.18 | <0.01 |
| Time since first exposurea | −0.04 | −0.08 to −0.00 | 0.049 |
| Time since first exposureb | 2.81 | 1.50 to 4.13 | <0.01 |
| Duration of exposurea | −0.79 | −1.50 to −0.08 | 0.029 |
| Mine or mill | 0.00 | ||
| Asbestos cement factory | −0.06 | −0.50 to 0.39 | 0.798 |
| Amosite factory | −0.73 | −1.49 to 0.02 | 0.058 |
| Railway workers | −1.44 | −1.94 to −0.94 | <0.01 |
| Environmental exposure | −0.89 | −1.19 to −0.58 | <0.01 |
| Crocidolite | 0.94 | 0.50 to 1.38 | <0.01 |
| Peritoneal mesothelioma | |||
| Sex | −0.72 | −1.19 to 0.24 | 0.003 |
| Time since first exposureb | 3.21 | 2.19 to 4.22 | <0.01 |
| Duration of exposureb | 0.79 | 0.55 to 1.04 | <0.01 |
| Mine or mill | 0.00 | ||
| Asbestos cement factory | −1.06 | −1.67 to −0.46 | <0.01 |
| Amosite factory | −2.17 | −3.41 to −0.93 | <0.01 |
| Railway workers | −3.83 | −4.75 to −2.91 | <0.01 |
| Environmental exposure | −2.56 | −3.45 to −1.66 | <0.01 |
Time since first exposure a=time since first exposure (λ (asbestos clearance)).
Time since first exposure b=ln (time since first exposure +1) (k (power)).
Duration of exposure a=duration of exposure−0.5.
Duration of exposure b=ln(duration of exposure+0.02) (0.02=1 week).