Unadjusted associations of SDB and other variables with hypertensive disorders of pregnancy (n=100)
| Variable | OR for pregnancy-induced hypertension (95% CI) | p Value |
|---|---|---|
| 1st trimester AHI | 1.04 (0.90 to 1.21) | 0.584 |
| 3rd trimester AHI | 0.96 (0.86 to 1.07) | 0.485 |
| 1st trimester OSA (AHI ≥5 events/h) | 0.44 (0.05 to 3.74) | 0.455 |
| 3rd trimester OSA (AHI ≥5 events/h) | 0.50 (0.13 to 1.90) | 0.310 |
| Change in AHI | 0.93 (0.82 to 1.06) | 0.270 |
| Age, 10 years | 0.52 (0.23 to 1.16) | 0.109 |
| 1st trimester BMI, 5 unit | 1.17 (0.84 to 1.64) | 0.348 |
| 3rd trimester BMI, 5 unit | 1.27 (0.87 to 1.84) | 0.220 |
| Gestational weight gain | 1.05 (0.95 to 1.15) | 0.347 |
| 1st trimester neck circumference | 1.13 (0.96 to 1.33) | 0.135 |
| 3rd trimester neck circumference | 1.10 (0.94 to 1.29) | 0.235 |
| Nulliparity (ref=multi) | 3.00 (1.03 to 8.67) | 0.043 |
| Prior history of hypertensive disorder of pregnancy | 1.29 (0.24 to 6.99) | 0.765 |
| White and other ethnicity (ref African–American) | 1.09 (0.35 to 3.40) | 0.883 |
The bold numbers are statistically significant at the <0.05 level.
AHI, Apnoea-Hypopnoea Index; BMI, Body Mass Index; OSA, obstructive sleep apnoea; SDB, sleep-disordered breathing.