Changes in immunological parameters pre- and post-intravenous antibiotics
| Total IgE (kUI/l) | Wilcoxon signed rank test | A fumigatus specific IgE (kUa/l) | Wilcoxon signed rank test | A fumigatus specific IgG (mg/l) | Wilcoxon signed rank test | ||||
|---|---|---|---|---|---|---|---|---|---|
| Pre | Post | Pre | Post | Pre | Post | ||||
| All patients (n=26) | 78 (28–230) | 62 (25–220) | Z=−0.47 p=0.64 | 1.5 (0.0–8.9) | 1.3 (0–7.7) | Z=−0.73 p=0.47 | 73 (50–112) | 63 (51–100) | Z=−1.82 p=0.07 |
| Patients with a fall in Aspergillus DNA (n=19) | 110 (28–250) | 79 (31–290) | Z=−1.19 p=0.24 | 7.8 (0.0–10.6) | 7.0 (0.0–8.1) | Z=−0.93 p=0.35 | 78 (65–113) | 75 (55–102) | Z=−1.50 p=0.13 |
| Patients with a fall in Aspergillus DNA and GM index (n=8) | 104 (14–293) | 61 (21–253) | Z=−1.68 p=0.09 | 0.6 | 0.6 | Z=0.00 p=1.00 | 118 (84–145) | 103 (72–143) | Z=−1.12 p=0.26 |
Values are shown as median (IQR).
GM, galactomannan.