Adjusted OR for the risk of wake-up stroke
| Covariate | OR (95% CI) | p Value |
|---|---|---|
| RLSh-LOSA | 1.91 (1.08 to 3.38) | 0.03 |
| Age | 1.00 (0.98 to 1.02) | 0.81 |
| Male sex | 0.95 (0.56 to 1.60) | 0.84 |
| Hypertension | 1.57 (0.89 to 2.80) | 0.12 |
| Diabetes | 1.24 (0.68 to 2.24) | 0.49 |
| Atrial fibrillation | 1.00 (0.48 to 2.11) | 1.00 |
| Antithrombotic therapy | 1.19 (0.69 to 2.07) | 0.53 |
RLSh-LOSA, patients with right to left shunt plus at least one episode of long obstructive sleep apnoea lasting 20 s or more.