Change over one decade in age, body mass index (BMI), forced expiratory volume in 1 s (FEV1)% predicted, diabetes mellitus, nutritional supplements, enteral feeding and the nine domains of the Cystic Fibrosis Quality of Life Questionnaire (CFQoL) for 91 patients with cystic fibrosis (CF) in the cohort (40 men and 51 women) with assessments separated by 10 years*
| Start of decade | End of decade | Decade change | ||||
|---|---|---|---|---|---|---|
| Age (years), mean (SD) | ||||||
| All | 25.1 | (7.5) | 34.9 | (7.6) | 9.8 | (0.5) |
| Men | 24.5 | (7.6) | 34.3 | (7.7) | 9.8 | (0.7) |
| Women | 25.5 | (7.5) | 35.4 | (7.5) | 9.9 | (0.3) |
| FEV1%, mean (SD) | ||||||
| All | 61.9 | (22.1) | 53.1 | (22.5) | −8.8 | (18.3) |
| Men | 65.9 | (20.1) | 55.3 | (22.2) | −10.6 | (13.4) |
| Women | 58.7 | (23.2) | 51.4 | (22.9) | −7.3 | (21.4) |
| BMI, mean (SD) | ||||||
| All | 21.4 | (2.8) | 21.5 | (2.9) | 0.1 | (1.7) |
| Men | 21.6 | (3.0) | 22.1 | (3.3) | 0.5 | (1.8) |
| Women | 21.3 | (2.7) | 21.1 | (2.5) | −0.2 | (1.7) |
| Diabetes, n (%) | ||||||
| All | 31 | (34) | 52 | (57) | 21 | (23) |
| Men | 10 | (25) | 24 | (60) | 12 | (35) |
| Women | 21 | (41) | 28 | (55) | 7 | (14) |
| Nutritional supplements, n (%) | ||||||
| All | 31 | (34) | 33 | (36) | 2 | (2) |
| Men | 20 | (50) | 17 | (43) | −3 | (−7) |
| Women | 11 | (22) | 16 | (31) | 5 | (9) |
| Enteral feeding, n (%) | ||||||
| All | 13 | (14) | 17 | (19) | 4 | (5) |
| Men | 5 | (12) | 8 | (16) | 3 | (4) |
| Women | 8 | (16) | 9 | (18) | 1 | (2) |
| Physical functioning, mean (SD) | ||||||
| All | 86.8 | (15.8) | 78.8 | (21.8) | −8.0 | (16.7) |
| Men | 89.3 | (14.6) | 81.7 | (19.2) | −7.6 | (13.7) |
| Women | 84.9 | (16.6) | 76.5 | (23.5) | −8.4 | (18.9) |
| Social functioning, mean (SD) | ||||||
| All | 87.6 | (16.4) | 78.4 | (26.2) | −9.2 | (21.9) |
| Men | 87.8 | (17.6) | 81.6 | (21.8) | −6.2 | (17.7) |
| Women | 87.5 | (15.5) | 75.8 | (29.1) | −11.7 | (24.6) |
| Emotional responses, mean (SD) | ||||||
| All | 80.9 | (20.5) | 72.6 | (23.1) | −8.3 | (18.8) |
| Men | 83.8 | (21.5) | 75.9 | (21.4) | −7.9 | (19.1) |
| Women | 78.7 | (19.6) | 69.9 | (24.3) | −8.8 | (19.0) |
| Treatment issues, mean (SD) | ||||||
| All | 80.1 | (20.6) | 66.4 | (22.0) | −13.7 | (19.9) |
| Men | 80.7 | (24.4) | 65.8 | (21.8) | −14.9 | (19.0) |
| Women | 79.6 | (17.4) | 66.9 | (22.4) | −12.7 | (20.7) |
| Chest symptoms, mean (SD) | ||||||
| All | 79.9 | (19.8) | 70.5 | (24.1) | −9.4 | (18.9) |
| Men | 81.4 | (22.6) | 71.6 | (23.7) | −9.8 | (15.6) |
| Women | 78.7 | (17.5) | 69.6 | (24.7) | −9.1 | (22.1) |
| Body image, mean (SD) | ||||||
| All | 70.1 | (23.0) | 64.1 | (26.1) | −6.0 | (15.2) |
| Men | 66.2 | (24.2) | 59.1 | (26.9) | −7.1 | (17.4) |
| Women | 73.3 | (21.8) | 68.0 | (25.0) | −5.3 | (13.3) |
| Interpersonal relationships, mean (SD) | ||||||
| All | 64.5 | (21.9) | 57.7 | (25.8) | −6.8 | (22.0) |
| Men | 69.0 | (22.8) | 61.8 | (25.5) | −7.2 | (22.7) |
| Women | 60.9 | (20.7) | 54.5 | (25.8) | −6.4 | (21.6) |
| Career concerns, mean (SD) | ||||||
| All | 65.5 | (26.4) | 49.6 | (32.5) | −15.9 | (23.3) |
| Men | 71.4 | (25.4) | 55.8 | (32.5) | −15.6 | (23.4) |
| Women | 61.0 | (26.6) | 44.7 | (31.9) | −16.3 | (23.3) |
| Concerns for the future, mean (SD) | ||||||
| All | 49.4 | (25.5) | 36.2 | (23.4) | −13.2 | (21.2) |
| Men | 56.4 | (25.1) | 42.0 | (25.6) | −14.4 | (21.1) |
| Women | 43.9 | (24.6) | 31.7 | (20.6) | −12.2 | (21.4) |
*The 91 patients comprised the 38 patients who had 10 years between first and last observations and 53 of the 64 patients who had 12 years between first and last observations (11 patients in the latter group were omitted because they did not have data separated by precisely 10 years).