Table 2

Baseline patient characteristics

Baseline physiological and functional measures
All patients (n=54)Patients with full datasets (n=28)Complete fissures (n=13)Incomplete fissures (n=15)Difference p value*
FEV1, litres0.92±0.32 (30.4±8.2% pred)1.02±0.35 (33.0±8.3% pred)
  • 0.98±0.40 (33.0±9.0% pred)

  • range 0.48 to 1.42

  • 1.05±0.29 (33.1±7.7% pred)

  • range 0.67 to 1.72

0.443
FVC, litres2.63±0.74 (64.1±13.2% pred)2.68±0.71 (66.0±12.5% pred)
  • 2.36±0.78 (61.2±13.7% pred)

  • range 1.33 to 4.03

  • 2.94±0.39 (70.4±10.5% pred)

  • range 2.25 to 4.41

0.008
RV, litres5.52±1.23 (242.4±62.3% pred)5.02±0.84 (227.0±50.3% pred)
  • 5.42±0.87 (259.3±37.0% pred)

  • range 3.66 to 6.39

  • 4.76±0.65 (202.3±45.9% pred)

  • range 3.72 to 6.14

0.035
TLC, litres8.28±1.26 (132.7±22.4% pred)7.84±0.97 (129.8±21.5% pred)
  • 7.94±1.19 (139.2±15.1% pred)

  • range 5.54 to 9.69

  • 7.76±0.77 (121.5±22.5% pred)

  • range 6.41 to 8.88

0.583
MRCD, U2.90±0.742.93±0.75
  • 3.1±0.76

  • range 2.0 to 4.0

  • 2.8±0.74

  • range 2.0 to 4.0

0.291
6MWT, m309.0±89.9328±90
  • 292±90

  • range 160 to 420

  • 347±75

  • range 216 to 529

0.057
  • * Comparison of patients with complete versus incomplete fissures performed by Student t test; significance defined as p≤0.008 when corrected for multiple comparisons.

  • 6MWT, 6 min walk test; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; MRCD, Medical Research Council Dyspnoea; pred, predicted; RV, residual volume; TLC, total lung capacity.