Characteristics of 80 COPD patients in stable condition and 20 healthy non-COPD volunteers
| Non-COPD volunteers (n=20) | Stable COPD (n=80) | p Value | |
| Age, years | 69.0±11.0 | 73.0±10.0 | 0.126 |
| Sex, male/female | 17/3 | 65/15 | 0.696 |
| Body mass index, kg/m2 | 24.2±3.44 | 22.1±4.47 | 0.051 |
| Lung function | |||
| FEV1, L | 2.72±0.58 | 1.66±1.00 | <0.001 |
| FEV1/FVC ratio, % | 77.3±6.20 | 56.4±25.2 | <0.001 |
| Predicted FEV1, % | 97.6±16.1 | 71.6±40.9 | <0.001 |
| LAA scores (n=83), median (range) | 4 (1–10) | 13 (2–24) | <0.001 |
| Physiological parameters | |||
| Systolic blood pressure, mm Hg | 118.0±21.0 | 122.0±21.0 | 0.425 |
| Diastolic blood pressure, mm Hg | 61.0±11.0 | 68.0±12.5 | 0.319 |
| PaO2, mm Hg (at sample correction) | 82.3±4.00 | 80.0±10.5 | 0.379 |
| Traditional risk factors | |||
| Pack-years smoking index, median (range) | 27.75 (1–100) | 40 (0–90) | 0.372 |
| Total cholesterol, mg/dl | 189.5±33.5 | 193.0±37.8 | 0.607 |
| Fasting glucose, mg/dl | 104.5±18.5 | 100.0±15.5 | 0.505 |
| Inflammatory markers | |||
| CRP, mg/dl | 0.100±0.000 | 0.200±0.300 | 0.084 |
| Leucocyte counts, /μl | 6100±1820 | 6300±2000 | 0.613 |
Bold denotes values: p < 0.05.
Values are the median±IQR unless stated otherwise.
Difference in the distribution of gender between the two groups was analysed using the χ2 test. Differences in other parameters were analysed using Mann–Whitney U test.