Table 3

IgG1 antibody titre stratified by asthma at 5 years of age

1 year old2 years old3 years old4 years old5 years old
P4
 Asthma1241 (605 to 2543)2771 (1133 to 6777)12 938 (6224 to 26 894)8334 (2926 to 23 738)10 812 (5605 to 20 859)
 No asthma1772 (1292 to 2431)5262 (3541 to 7820)14 167 (10 764 to 18 645)18 648 (12 287 to 28 301)26 358 (19 658 to 35 341)
 p Value0.48180.27060.77130.16670.0081
P6
 Asthma353 (260 to 480)423 (257 to 697)2499 (1068 to 5847)900 (465 to 1741)1440 (750 to 2766)
 No asthma461 (380 to 559)853 (659 to 1105)4881 (3776 to 6308)3060 (2253 to 4156)3438 (2640 to 4475)
 p Value0.55560.02480.03180.00250.0099
PspA (1 and 2)
 Asthma1235 (800 to 1905)1951 (966 to 3941)7983 (3254 to 19 584)11 159 (3678 to 33 854)28 167 (9531 to 83 242)
 No asthma1397 (1167 to 1673)3144 (2291 to 4313)14 600 (10 449 to 20 401)20 777 (13 360 to 32 313)37 611 (24 638 to 57 413)
 p Value0.41360.16480.19060.22580.5736
PspC
 Asthma1839 (1104 to 3062)38 192 (14 143 to 103 133)234 369 (93 344 to 588 457)321 962 (153 239 to 676 456)43 257 (212 726 to 878 745)
 No asthma2758 (2142 to 3553)96 051 (67 665 to 136 346)214 956 (151 420 to 305 154)345 056 (253 117 to 470 391)493 713 (385 567 to 632 192)
 p Value0.25880.05820.80110.75480.9737
  • The value is the geometric mean of the IgG1 antibody titre (ng/ml) with the CI of antibody binding in parentheses.

  • Comparisons between SPT-positive and SPT-negative groups by the Mann–Whitney test are shown.

  • p Values <0.0125 are considered significant after correcting for multiple testing.