IgG1 antibody titre stratified by HDM sensitisation (SPT-positive or SPT-negative at 5 years of age)
| 1 year old | 2 years old | 3 years old | 4 years old | 5 years old | |
| P4 | |||||
| SPT+ | 1022 (666 to 1522) | 2617 (1494 to 4583) | 10 458 (6676 to 16 383) | 16 698 (8532 to 32 681) | 20 447 (12 932 to 32 330) |
| SPT− | 2168 (1483 to 3168) | 6393 (4044 to 10 106) | 16 391 (12 020 to 22 353) | 16 423 (10 123 to 26 643) | 23 354 (16 594 to 32 866) |
| p Value | 0.0406 | 0.0353 | 0.1010 | 0.9597 | 0.4891 |
| P6 | |||||
| SPT+ | 303 (256 to 358) | 531 (376 to 750) | 2337 (1549 to 3525) | 1521 (977 to 2368) | 2151 (1399 to 3309) |
| SPT− | 538 (425 to 683) | 922 (682 to 1246) | 6086 (4499 to 8233) | 3297 (2295 to 4737) | 3419 (2515 to 4648) |
| p Value | 0.0056 | 0.0434 | <0.001 | 0.0122 | 0.0487 |
| PspA (1 and 2) | |||||
| SPT+ | 1310 (997 to 1720) | 2222 (1437 to 3437) | 8144 (4902 to 13 530) | 13 317 (6724 to 26 373) | 24 524 (11 799 to 50 974) |
| SPT− | 1406 (1141 to 1733) | 3347 (2308 to 4854) | 16 657 (11 297 to 24 560) | 22 581 (13 473 to 37 846) | 42 513 (26 510 to 68 174) |
| p Value | 0.7825 | 0.2986 | 0.0234 | 0.2498 | 0.1971 |
| PspC | |||||
| SPT+ | 2391 (1632 to 3504) | 39 702 (20 983 to 75 121) | 144 959 (76 288 to 275 444) | 254 361 (151 998 to 425 663) | 419 481 (250 989 to 701 081) |
| SPT− | 2719 (2040 to 3625) | 118 443 (81 380 to 172 387) | 263 382 (182 130 to 380 882) | 396 132 (280 887 to 558 661) | 516 873 (402 468 to 663 797) |
| p Value | 0.6685 | 0.0042 | 0.1644 | 0.1463 | 0.8886 |
The value is the geometric mean of the IgG1 antibody titre (ng/ml) with the CI of antibody binding in parentheses.
Comparisons between SPT-positive and SPT-negative groups by the Mann–Whitney test are shown.
p Values <0.0125 are considered significant after correcting for multiple testing.
HDM, house dust mite; SPT, skin prick test.