Table 2

Combined p values for replication of FGF7 SNPs

SNPCOPD consortium OR (two-sided p value)Lovelace (all subjects) OR (one-sided p value)Lovelace (Hispanics) OR (one-sided p value)Combined one-sided p value (all subjects)Combined one-sided p value (Hispanics only)*
rs125913001.27 (8.78E–6)1.21 (0.01)1.5 (0.06)7.9E–73.9E–6
rs44807401.27 (6.75E–6)1.15 (0.05)1.64 (0.025)2.8E–61.5E–6
  • * Fisher's combined p value using original two-sided p values.

  • COPD, chronic obstructive pulmonary disease; FGF7, fibroblast growth factor-7; SNP, single nucleotide polymorphism.