Baseline and post-walk systemic inflammatory mediators in patients with Chronic Obstructive Pulmonary Disease (COPD) and healthy comparators
| Marker | Rest concentration | Post walk concentration | p Value |
| COPD (n=16) | |||
| CRP (mg/l) | 3.77 (1.67 to 8.49) | 4.75 (1.99 to 11.08) | 0.56 |
| IL-6 (pg/ml) | 2.80 (2.00 to 3.25) | 2.95* (2.03 to 3.63) | 0.04 |
| TNF-α (pg/ml) | 8.25 (5.80 to 10.13) | 7.10 (4.95 to 10.03) | 0.64 |
| IL-17 (pg/ml) | 52.52 (35.92 to 82.61) | 55.16 (47.85 to 79.17) | 0.62 |
| Healthy (n=16) | |||
| CRP (mg/l) | 1.15 (0.61 to 2.60) | 1.60 (0.68 to 2.60) | 0.72 |
| IL-6 (pg/ml) | 2.70 (2.00 to 3.00) | 2.00 (2.00 to 2.95) | 0.73 |
| TNF-α (pg/ml) | 5.15 (4.00 to 9.18) | 7.05 (4.00 to 9.08) | 0.64 |
| IL-17 (pg/ml) | 65.50 (52.20 to 82.43) | 70.40 (57.78 to 88.28) | 0.31 |
↵* p<0.05 compared with rest concentration in the COPD group; all baseline concentrations (between groups) and other pre-post changes (within groups) were not significantly different (p>0.05).
COPD, chronic obstructive pulmonary disease; CRP, C-reactive protein, IL-6, Interleukin-6, TNF-α, IL-17, Interleukin-17; mg/l, milligrammes per Litre; pg/ml, picogrammes per millilitre.