Per-protocol univariate and multivariate analyses of survival with Cox proportional hazards regression models
| Univariate analysis | Multivariate analysis | |||
| HR (95% CI) | p Value | HR (95% CI) | p Value | |
| Rehabilitation | 0.279 (0.078 to 0.990) | 0.048 | 0.267 (0.075 to 0.954) | 0.042 |
| Female | 1.514 (0.517 to 4.429) | 0.449 | 0.839 (0.278 to 0.954) | 0.755 |
| Age | 1.032 (0.975 to 1.092) | 0.283 | 1.030 (0.971 to 1.093) | 0.321 |
| FFMI, +1 kg/m2 | 0.831 (0.654 to 1.055) | 0.128 | Not included in multivariable model | |
| FEV1/FVC, +1 | 0.959 (0.911 to 1.010) | 0.110 | Not included in multivariable model | |
| Albumin, +1 g/l | 0.930 (0.833 to 1.038) | 0.194 | Not included in multivariable model | |
| Pao2, +1 kPa | 0.613 (0.408 to 0.920) | 0.018 | Not included in multivariable model | |
| 6MWD, +1% predicted | 0.973 (0.948 to 0.999) | 0.040 | Not included in multivariable model | |
| Pmax, +1 W | 0.948 (0.900 to 0.9996) | 0.048 | Not included in multivariable model | |
| Time to exhaustion, +1 min | 0.997 (0.995 to 0.9998) | 0.034 | 0.997 (0.995 to 0.9998) | 0.035 |
6MWD, 6-min walking distance; FEV1, forced expiratory volume in 1 s; FFMI, fat-free mass index; FVC, forced vital capacity; Pmax, peak workload on bicycle; Pao2, arterial oxygen tension.