Abstract P110 Table 1
FLUT/FORM vs FORM*
FLUT/FORM (N=341)FORM (N=345)
Mean FEV1 at baseline, L (SD)2.33 (0.60)2.34 (0.62)
Pre-dose at study end
 N341345
 Mean FEV1, L (SD)2.53 (0.71)2.4 (0.76)
 LS mean change, L (95% CI)†0.19 (0.15 to 0.24)0.06 (0.02 to 0.10)
FLUT/FORM vs FLUT‡
FLUT/FORM (N=641)FLUT (N=643)
Mean FEV1 at baseline, L (SD)2.11 (0.62)2.11 (0.65)
2 h post-dose at study end
 N629613
 Mean FEV1, L (SD)2.52 (0.78)2.38 (0.75)
 LS mean change, L (95% CI)†0.41 (0.38 to 0.44)0.27 (0.23 to 0.30)

  • Study end was at week 8 or 12.

  • Analysis of covariance was calculated with treatment and baseline pre-dose forced expiratory volume at 1 s as covariates, and centre as a random effect.

  • ↵* Pooled analysis from three studies to include only studies with treatment arms of equivalent nominal doses to FLUT/FORM.

  • ↵† Least-squares mean change from baseline.

  • ↵‡ Pooled analysis from five studies to include only studies with treatment arms of equivalent nominal doses to FLUT/FORM.

  • FLUT, fluticasone propionate; FORM, formoterol fumarate.