Table 1

Univariate associations with asthma remission by the age of 46 years

Characteristic or exposure (n)Remitted, n (%)OR (95% CI)p Value
Sex
 Female (878)528 (44.9)0.66 (0.54 to 0.80)<0.001
 Male (933)649 (55.1)1.00
Maternal asthma
 Yes (301)179 (59.5)0.74 (0.57 to 0.96)0.021
 No (1405)934 (66.5)1.00
Paternal asthma
 Yes (288)185 (64.2)0.94 (0.72 to 1.22)0.633
 No (1388)912 (65.7)1.00
Maternal smoking
 Yes (640)408 (63.8)0.90 (0.73 to 1.10)0.303
 No (1071)709 (66.2)1.00
Paternal smoking
 Yes (988)640 (64.8)0.93 (0.75 to 1.14)0.460
 No (687)457 (66.5)1.00
Allergic rhinitis
 Childhood onset (400)256 (64.0)0.45 (0.33 to 0.61)<0.001
 Later onset (853)497 (58.3)0.35 (0.27 to 0.46)<0.001
 None (495)395 (79.8)1.00
Eczema
 Childhood onset (381)233 (61.2)0.65 (0.50 to 0.83)0.001
 Later onset (582)343 (58.9)0.59 (0.47 to 0.74)<0.001
 None (848)601 (70.9)1.00
Food allergy
 Yes (187)116 (62.0)0.84 (0.62 to 1.15)0.289
 No (1582)1043 (66.0)1.00
Urticaria
 Yes (427)280 (65.6)1.01 (0.80 to 1.27)0.949
 No (1321)864 (65.4)1.00
Childhood chronic bronchitis
 Yes (328)206 (62.8)0.68 (0.52 to 0.89)0.005
 No (873)622 (71.3)1.00
Severe childhood asthma
 Yes (376)254 (67.6)1.15 (0.91 to 1.47)0.249
 No (1434)923 (64.4)1.00
Exclusive breast feeding
 Yes (703)462 (65.7)1.02 (0.84 to 1.25)0.812
 No (1068)696 (65.2)1.00
At least one older sibling
 Yes (1180)779 (66.0)1.14 (0.93 to 1.39)0.211
 No (631)398 (63.1)1.00
Childhood pneumonia
 Yes (376)265 (70.5)1.34 (1.04 to 1.71)0.021
 No (1387)889 (64.1)1.00
Childhood immunisation (DPT)
 Yes (1512)971 (64.2)0.85 (0.58 to 1.24)0.394
 No (131)89 (67.9)1.00
Impaired lung function (at age 7 years)
 Yes (72)38 (52.8)0.59 (0.37 to 0.94)0.028
 No (1739)1139 (65.5)1.00
Body mass index (at age 7 years)
 Obese (9)5 (55.6)0.66 (0.18 to 2.48)0.540
 Overweight (100)66 (66.0)1.03 (0.67 to 1.58)0.897
 Normal (1585)1036 (65.4)1.00
Life stage at asthma onset
 Childhood (1192)880 (73.8)3.28 (2.62 to 4.10)<0.001
 Adolescence (148)75 (50.7)1.19 (0.82 to 1.73)0.351
 Adult (456)211 (46.3)1.00
Adult smoking
 Ever smoking (1096)716 (65.3)1.04 (0.85 to 1.26)0.718
 Never smoking (707)456 (64.5)1.00
Passive adult smoking
 Yes (501)316 (63.1)0.89 (0.72 to 1.11)0.306
 No (1278)839 (65.7)1.00
Childhood socio-economic status
 Level 1 (369)244 (66.1)1.00
 Level 2 (108)69 (63.9)0.91 (0.58 to 1.42)0.667
 Level 3 (520)337 (64.8)0.94 (0.71 to 1.25)0.684
 Level 4 (473)319 (67.4)1.06 (0.79 to 1.42)0.687
 Level 5 (229)136 (59.4)0.75 (0.53 to 1.05)0.097
Adult socio-economic status
 Level 1 (515)338 (65.6)1.00
 Level 2 (202)131 (64.9)0.97 (0.69 to 1.36)0.988
 Level 3 (325)230 (70.8)1.27 (0.94 to 1.71)0.338
 Level 4 (343)216 (63.0)0.89 (0.67 to 1.18)0.425
 Level 5 (403)251 (62.3)0.86 (0.66 to 1.13)0.294
  • Results with a p value <0.15 are shown in bold.

  • DPT, diphtheria, pertussis and tetanus.