Baseline patient characteristics and 11478G→A genotype in COPD; data are expressed as mean (95% CI) or %
| GG | GA/AA | p Value | |
| FEV1 (litres) | 1.14 (1.06 to 1.23) | 1.33 (1.16 to 1.50) | 0.024 |
| FEV1 (% predicted) | 47.0 (43.9 to 50.1) | 54.4 (47.0 to 61.8) | 0.069 |
| FVC (litres) | 2.43 (2.29 to 2.57) | 2.82 (2.47 to 3.17) | 0.029 |
| FEV1/FVC | 48% (44 to 50) | 48% (44 to 52) | 0.974 |
| Smoking (pack-years) | 52.3 (45.9 to 58.7) | 49.6 (33.4 to 65.9) | 0.457 |
| BMI (kgm-2) | 26.1 (25.1 to 27.0) | 26.0 (23.9 to 28.0) | 0.782 |
| Current smoker | 26% | 29% | 0.735 |
BMI, body mass index; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.