11478G→A genotype frequencies in control subjects and patients with COPD, and patients with COPD who were frequent and infrequent exacerbators in the London COPD cohort
| COPD (n=204) | Controls (n=65) | χ2 p value | |
| GG (wild type) | 169 (83%) | 56 (86%) | 0.35 |
| GA | 33 (16%) | 8 (12%) | |
| AA | 2 (1%) | 1 (2%) | |
| HWE p value | 0.78 | 0.28 |
| COPD frequent exacerbators (n=69) | COPD infrequent exacerbators (n=135) | χ2 p value | |
| GG (wild type) | 59 (86%) | 110 (82%) | 0.32 |
| GA | 9 (15%) | 24 (18%) | |
| AA | 1 (2%) | 1 (1%) | |
| HWE p value | 0.36 | 0.80 |
COPD, chronic obstructive pulmonary disease; HWE, Hardy–Weinberg equilibrium.