Table 1

Baseline characteristics of patients with N1 lymph node involvement in SEER-Medicare

CharacteristicLymph node ratiop Value
≤0.15 (N=524)0.16–0.50 (N=849)≥0.5 (N=309)
Age (years), N (%)
 ≤70191 (36)303 (36)108 (35)0.980
 71–75165 (31)279 (32)103 (33)
 >75168 (32)267 (31)98 (32)
Female, N (%)200 (38)379 (45)171 (55)<0.0001
Race/ethnicity, N (%)
 White483 (92)744 (88)270 (87)0.061
 African American18 (3)35 (4)18 (6)
 Hispanic/other*23 (4)70 (8)21 (7)
 Married, N (%)326 (62)531 (63)179 (58)0.338
Median income in ZIP code of residence, N (%)
 Lowest quartile127 (24)186 (22)73 (23)0.682
 Second quartile128 (24)221 (26)69 (22)
 Third quartile126 (24)223 (26)87 (28)
 Highest quartile143 (27)215 (25)80 (26)
Comorbidity score, N (%)
 ≤1190 (36)339 (40)117 (38)0.445
 1–2195 (37)290 (34)120 (39)
 >2139 (27)220 (26)72 (23)
Tumour status, N (%)
 T1A61 (12)95 (11)28 (9)0.364
 T1B82 (16)148 (17)59 (19)
 T2A234 (45)388 (46)152 (49)
 T2B54 (10)98 (12)32 (10)
 T393 (18)120 (14)38 (12)
Histology, N (%)
 Adenocarcinoma222 (42)408 (48)175 (57)0.001
 Squamous cell carcinoma219 (42)293 (35)81 (26)
 Large cell carcinoma32 (6)62 (7)17 (6)
 Bronchioloalveolar cell carcinoma29 (6)49 (6)25 (8)
 Other22 (4)37 (4)11 (4)
Tumour location, N (%)
 Upper lobe287 (55)450 (53)149 (48)0.118
 Lower lobe186 (36)337 (40)128 (41)
 Other location51 (10)62 (7)32 (10)
Type of surgery, N (%)
 Lobectomy410 (78)722 (85)281 (91)<0.0001
 Pneumonectomy114 (22)127 (15)28 (9)
Postoperative radiation therapy, N (%)
 Yes135 (26)362 (43)158 (51)<0.0001
 No389 (74)487 (57)151 (49)
Adjuvant chemotherapy, N (%)
 Yes88 (17)177 (21)69 (22)0.091
 No436 (83)672 (79)240 (78)
  • * Categories were combined to avoid reporting cells with small numbers of patients.

  • Income data missing for four study subjects.