Table 4

Relationship between total vitamin D intake and FEV1 (n=2942) and FVC, FEV1/FVC and COPD (n=2936)

FEV1FEV1/FVC
Regression coefficient (l)*95% CIp ValueRegression coefficient*95% CIp Value
Fifths of vitamin D intake:
1 (lowest)
2−0.008(−0.061 to 0.045)0.7700.001(−0.009 to 0.010)0.897
30.001(−0.053 to 0.056)0.9630.005(−0.005 to 0.014)0.307
40.042(−0.015 to 0.099)0.1470.007(−0.003 to 0.017)0.157
5 (highest)0.079(0.017 to 0.141)0.0120.014(0.003 to 0.025)0.010
Effect per quintile increase in vitamin D intake0.020(0.006 to 0.034)0.0070.003(0.001 to 0.006)0.008
FVCCOPD
Regression coefficient (l)*95% CIp ValueOR*95% CIp Value
Fifths of vitamin D intake:
1 (lowest)
2−0.003(−0.065 to 0.060)0.9310.903(0.644 to 1.266)0.553
3−0.015(−0.078 to 0.049)0.6440.913(0.650 to 1.281)0.597
40.031(−0.036 to 0.098)0.3600.827(0.572 to 1.197)0.314
5 (highest)0.056(−0.016 to 0.128)0.1280.570(0.375 to 0.866)0.008
Effect per quintile increase in vitamin D intake0.014(−0.003 to 0.031)0.1090.894(0.814 to 0.983)0.020
  • * Adjusted for energy intake, smoke in home, smoker status, pack years, age left education, home ownership status, no. of rooms, no. of cars, social class, fat mass, activity score, alcohol, dietary supplement use, birth weight, father's social class at birth, inhaled or oral steroids use and paracetamol use. Age, height and gender were also included in the COPD analyses.

  • COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; 25(OH)D, 25 hydroxy vitamin D.