Table 1

Descriptive data and associations between lung function and the IL6-174G/C single nucleotide polymorphism

IL6-174G/C
GGGCCCβ (SE)p Value adjusted for birth weight
n14319787
Age (years)24.5 (0.4)24.3 (0.3)25.3 (0.5)
Sex (M/F)70/7383/11442/45
Traits
FEV1 (% predicted)*101.2 (1.1)103.2 (1.0)100.3 (1.1)–0.19 (0.95)0.839
FVC (% predicted)*106.4 (1.1)105.2 (1.0)100.9 (1.3)–2.18 (1.02)0.034
FEV1/FVC82.2 (0.7)84.8 (0.6)86.1 (0.7)1.83 (0.61)0.003
  • Data are mean (SE).

  • * The percentage predicted values were calculated according to reference equations.2

  • F, female; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; M, male.