Demographic and clinical characteristics of patients (N=9)
| Drug-susceptible TB (n=5) | Drug-resistant TB (n=4) | |
| Median age in years (range) | 2.5 (1.6 to 5) | 10.5 (5 to 13) |
| Female gender (%) | 2 (40%) | 4 (100%) |
| Known TB contact | 4 (80%) | 4 (100%) |
| Chest x-ray findings on presentation | Hilar LAD only: 3 (60%) LAD + infiltrates: 2 (40%) | Hilar LAD only: 1 (25%) LAD + infiltrates: 3 (75%) |
| Median baseline ALS titre, in optical density units (range) | 1.421 (0.412 to 2.070) | 0.615 (0.380 to 1.532) |
| Resolution of fever by 2 months | 3 (75%)* | 0 (0%) |
| Resolution of cough by 2 months | 4 (80%) | 1 (25%) |
| Median change in BMI for age/gender over 2 months (range) | 1.18 (−1.06 to 4.15) | 0.48 (0.01 to 0.57) |
| Median change in BMI for age/gender over 6 months (range) | 2.1 (1.01 to 4.95) | 0.6 (−0.5 to 0.7) |
| Median change in ALS titre over 2 months, in optical density units (range) | −0.690 (−1.452 to −0.152) | 0.041 (−0.421 to 0.077) |
| Median change in ALS titre over 6 months, in optical density units (range) | −1.151 (−1.636 to −0.214) | −0.057 (−0.664 to 0.100) |
↵* Of the four children with drug-susceptible TB who presented with fevers.
ALS, antibodies in lymphocyte supernatant; BMI, body mass index; LAD, lymphadenopathy; TB, tuberculosis.