Table 5

Aetiology according to severity score (CURB-65) (number of patients with known aetiology in specific risk class)

AetiologyCURB-65 0–1 (n=741)CURB-65 2 (n=414)CURB-65 3–5 (n=308)Total (n=1463)p Value
Streptococcus pneumoniae291 (39)180 (43)142 (46)613 (42)0.092
Haemophilus influenzae32 (4)23 (6)15 (5)70 (5)0.638
Moraxella catarrhalis1 (0.1)1 (0.2)3 (1)5 (0.3)0.097
Atypical bacteria* 182 (25)58 (14)23 (7)263 (18)<0.001
Legionella pneumophila65 (9)36 (9)17 (6)118 (8)0.182
Mycoplasma pneumoniae* 55 (7)7 (2)3 (1)65 (4)<0.001
Chlamydophila pneumoniae36 (5)12 (3)2 (1)50 (3)0.002
Coxiella burnetii* 26 (4)3 (1)1 (0.3)30 (2)<0.001
Virus81 (11)43 (10)24 (8)148 (10)0.301
Staphylococcus aureus8 (1)11 (3)6 (2)25 (2)0.131
 MS* 2 (0.3)7 (2)5 (2)14 (1)0.024
 MR6 (1)4 (1)1 (0.3)11 (1)0.594
GNEB 10 (1)4 (1)13 (4)27 (2)0.002
Pseudomonas aeruginosa* 11 (1)18 (4)21 (7)50 (3)<0.001
Mixed101 (14)61 (15)46 (15)208 (14)0.806
Others24 (3)15 (4)15 (5)54 (4)0.441
  • Data are expressed as n (%).

  • * p<0.005, CURB-65 classes 0–1 vs 2.

  • p<0.005, CURB-65 classes 0–1 vs 3–5.

  • p<0.005, CURB-65 class 2 vs 3–5.

  • GNEB, Gram-negative enteric bacilli; MR, methicillin-resistant; MS, methicillin-sensitive.