Accuracy of two-stage diagnostic model (OSA50 score ≥5 and ApneaLink 3%ODI ≥16/h) for identifying moderate to severe OSA
| Moderate to severe OSA (AHI ≥30/h) | ||
| Development group | Validation group | |
| Sensitivity | 0.97 (0.81 to 1.00) | 0.88 (0.60 to 0.98) |
| Specificity | 0.87 (0.74 to 0.95) | 0.82 (0.70 to 0.90) |
| PPV | 0.83 (0.66 to 0.93) | 0.56 (0.35 to 0.75) |
| NPV | 0.98 (0.86 to 1.00) | 0.96 (0.86 to 0.99) |
| LR+ | 7.57 (3.58 to 16.03) | 4.93 (2.80 to 8.70) |
| LR− | 0.04 (0.01 to 0.26) | 0.15 (0.04 to 0.56) |
Data are presented as estimate (95% CI).
AHI, apnoea-hypopnoea index; LR, likelihood ratio; NPV, negative predictive value; ODI, oxygen desaturation index; OSA, obstructive sleep apnoea; PPV, positive predictive value.