Inflammatory mediator concentration in BAL fluid
| Mediator (pg/ml) | Respiratory virus (+) n=32 | Respiratory virus (–) n=32 | p Value |
| IL-1 | 6.35 (3.09–31.22) | 6.58 (1.24–36.65) | 0.552 |
| IL-1α | 534.55 (292.43–1753.36) | 524.84 (326.94–1040.44) | 0.501 |
| IL-2 | Not detected | Not detected | |
| IL-4 | Not detected | Not detected | |
| IL-5 | Not detected | Not detected | |
| IL-6 | 22.79 (4.09–194.46) | 32.46 (5.16–310.08) | 0.981 |
| IL-7 | 1.61 (1.19–2.10) | 1.66 (1.36–2.78) | 0.390 |
| IL-8 | 360.61 (161.00–1592.96) | 204.85 (68.92–1264.6) | 0.464 |
| IL-9 | 7.98 (2.68–14.44) | 3.24 (0.63–9.61) | 0.085 |
| IL-10 | 4.00 (2.49, 7.91) | 2.945 (1.33–4.64) | 0.170 |
| IL-12 | 5.45 (3.31–9.45) | 4.25 (2.04–5.94) | 0.065 |
| IL-13 | 1.856 (1.24–3.18) | 1.75 (0.975–2.85) | 0.435 |
| IL-15 | 1.82 (0.07–8.94) | 0.915 (0.2–2.88) | 0.363 |
| IL-17 | 6.20 (0–24.48) | Not detected | |
| Basic FGF | Not detected | Not detected | |
| Eotaxin-1 | 6.98 (4.71–25.94) | 5.39 (2.44–11.78) | 0.017 |
| G-CSF | 23.55 (7.85–97.77) | 14.26 (6.45–76.03) | 0.421 |
| GM-CSF | Not detected | Not detected | |
| IFNγ | 12.21 (2.95–34.84) | 9.81 (0.99–19.57) | 0.144 |
| IP-10 | 8902.33 (2059.07–57015.20) | 1246.82 (305.73–4811.82) | <0.001 |
| CCL2/MCP-1 | 259.50 (61.71–1583.27) | 240.03 (19.33–578.28) | 0.296 |
| CCL3/MIP-1α | Not detected | Not detected | |
| CCL4/MIP-1β | 60.55 (29.16–179.11) | 44.00 (27.72–87.79) | 0.115 |
| PDGF-BB | 12.94 (6.38–20.60) | 11.80 (4.81–19.00) | 0.838 |
| CCL5/RANTES | 66.39 (25.41–119.57) | 31.59 (11.23–97.15) | 0.385 |
| TNFα | 9.98 (0–24.57) | 1.63 (0–7.07) | 0.108 |
| VEGF | 36.42 (15.13–80.55) | 35.37 (12.25–70.86) | 0.995 |
Values were expressed as median (IQR).
Not detected indicates the level was beneath the lower limit of detection of the assay.
BAL, bronchoalveolar lavage; FGF, fibroblast growth factor; G-CSF, granulocyte colony-stimulating factor; GM-CSF, granulocyte–macrophage colony-stimulating factor IFNγ, interferon γ; IL, interleukin; IP-10, interferon γ-inducible protein 10; MCP, monocyte chemoattractant protein; MIP, macrophage inflammatory protein; PDGF, platelet-derived growth factor; RANTES, regulated on activation normal T cell expressed and secreted; TNFα, tumour necrosis factor α; VEGF, vascular endothelial growth factor.