Combined abstinence rates for the four interventions groups and associated intervention costs
| 12-month continuous abstinence rates* | 12-month point prevalence rates* | Weighted† average intervention costs 2007, €‡ (min–max) | |||
| Average rate | Difference with usual care (95% CI) | Average rate | Difference with usual care (95% CI) | ||
| Usual care | 1.4% | – | 6.8% | – | 0 |
| Minimal or brief counselling <90 min | 2.6% | 1.2% (−1.3% to 3.7%) | 9.0% | 2.2% (−3.4% to 7.7%) | 89 (22–112) |
| Intensive counselling ≥90 min | 6.0% | 4.6% (1.8% to 7.4%) | 12.3% | 5.5% (−1.6% to 12.6%) | 205 (93–264) |
| Intensive counselling ≥90 min with pharmacotherapy | 12.3% | 10.9% (6.9% to 15.0%) | 19.0% | 12.2% (0.5% to 23.9%) | 305 (130–452) |
↵* Based on random effect meta-analysis performed on the absolute abstinence rates in trial arms.
↵† Weighted by number of patients in the study.
↵‡ Calculated based on resource use as described in the individual papers valued using the following unit costs: general practitioner €2.10/min, respiratory physician €5.90/min, respiratory nurse €0.90/min, information material €1.00, 12 weeks NRT patches €194, 12 weeks NRT tablets €190, 12 weeks NRT gum €178, bupropion €1.30/tablet, nortriptyline €0.16/tablet.