Baseline characteristics of study participants
| Study participants (n=19) | |
| Age (years), mean±SD | 10.5±3.1 |
| Female/male | 12/7 |
| Pseudomonas aeruginosa +ve | 7 |
| Body mass index, mean±SD | 17.0±3.0 |
| Pancreatic insufficient, % | 84 |
| ΔF508/ΔF508, % | 42 |
| ΔF508 compound heterozygous % | 21 |
| FVC % predicted, mean ± SD (range) | 101±11.3 (81–121) |
| FEV1 % predicted, mean ± SD (range) | 96±12 (80–118) |
| FEF25–75% predicted, mean ± SD (range) | 84±24 (53–120) |
Pseudomonas aeruginosa +ve is defined as two or more positive cultures in the previous year and/or currently on inhaled antipseudomonal treatment.
% Predicted spirometry values were calculated using the equations of Weng et al.19
FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; FEF25–75, forced expiratory flow at 25–75% of the forced vital capacity.