Table 3

Predictive value of FENO and specific IgE on ‘wheezing’ (with mutual adjustment and adjustment for clinical history)*

FENOSpecific IgE
n=185
FENO and IgE both available
1.65
(95% CI 0.94 to 2.89) p=0.078
2.86
(95% CI 1.38 to 5.91) p=0.005
n=848
Total eligible population
1.57
(95% CI 1.10 to 2.23) p=0.016
2.78
(95% CI 1.90 to 4.07) p<0.001
  • ORs (95% CI) of FENO and specific IgE on the outcome of ‘wheezing’, using complete case data (n=185) and multiple imputed data (n=848).

  • * ORs for FENO and specific IgE were mutually adjusted for each other, and for three variables on clinical history (allergic mother/doctor's diagnosis of eczema/wheezing at age 4).

  • ORs for FENO are calculated per IQR increase in 10log-transformed FENO.

  • FENO, fraction of exhaled nitric oxide; IgE, immunoglobulin E; Rint, interrupter resistance.