Table 1

Baseline characteristics of the study population

Analysis sample (n = 20)Randomised (n = 28)Completed challenge (n = 38)
Mean age in years (SD)13.2 (2.36)13.3 (2.24)12.5 (2.49)
Mean weight in kg (SD)41.1 (11.2)41.7 (10.6)40.9 (11.5)
Mean height in cm (SD)149 (13.9)151 (13.8)150 (15.9)
Number of females (%)14 (70)18 (64)21 (55)
Mean FEV1 in litres (SD)1.67 (0.50)1.80 (0.57)1.76 (0.58)
Mean FEV1 % predicted (SD)64.4 (10.4)67.2 (12.0)67.5 (11.8)
Sputum microbiology*
Pseudomonas aeruginosa4 (22%)
Staphylococcus aureus2 (11%)
Sternotrophomonas maltophilia2 (11%)
Aspergillus fumigatus5 (28%)
  • *Results available for 18 patients in the analysis sample.

  • FEV1, forced expiratory volume in 1 s.