Daytime evaluation
| Zurich 490 m | Davos Schatzalp 1860 m | Davos Jakobshorn 2590 m | |||
| 1st day | 2nd day | 1st day | 2nd day | ||
| Spo2 (%) | 95 (94–96) | 93* (92–94) | 94* (93–94) | 91* (90–93) | 92* (91–93) |
| Weight (kg) | 98.8 (82.7–110.6) | 98.0* (83.5–109) | 98.5* (84–108) | 99.0* † ‡ (85.0–112.0) | 100.0* † ‡ (84–110) |
| Heart rate (1/min) | 61 (57–66) | 72* (66–77) | 73* (69–77) | 74* (64–80) | 74* (64–78) |
| Systolic blood pressure (mm Hg) | 130 (120–140) | 143* (135–156) | 145* (132–152) | 144* (132–160) | 144* (130–162) |
| Diastolic blood pressure (mm Hg) | 85 (80–90) | 86 (80–92) | 86 (80–95) | 85 (81–90) | 90 (81–97) |
| Peripheral oedema§ | 0 (0–0) | 0* (0–2) | 0* (2–2) | 0* (0–2) | 0* (0–2) |
| Driving simulator reaction time (s) | 3.4 (2.3–10.0) | 3.1 (2.5–10.0) | 2.9 (2.3–4.3) | 10.0 (2.7–10.0) | 10.0‡ (3.0–10.0) |
| Driving simulator tracking error | 0.38 (0.32–0.55) | 0.42 (0.34–0.55) | 0.40 (0.30–0.47) | 0.70* † ‡ (0.51–0.90) | 0.67* † ‡ (0.49–0.89) |
| Lake Louise acute mountain sickness score | 2.5 (2.0–4.0) | 3.0 (2.0–4.0) | 2.0 (1.0–3.0) | 4.0‡ (3.0–5.0) | 3.0‡ (2.0–5.0) |
| Difficulty sleeping§ | 1 (1–2) | 1 (1–1) | 1† (0–1) | 1.5‡ (1–2) | 1 (1–2) |
| Karolinksa sleepiness score | 4 (3–6) | 3* (3–4) | 3* (2–3) | 3 (3–4) | 3 (2–3) |
Data were obtained in the morning after sleep studies. Values are median (IQR).
↵* p<0.01 vs 490 m.
↵† p<0.005 vs 1860 m, day 1.
↵‡ p<0.005 vs 1860 m, day 2.
↵§ Peripheral oedema was rated as part of the Lake Louise acute mountain sickness protocol with 0 (absent), 1 (at one location) or 2 points (at two or more locations). Difficulty sleeping was also rated within the Lake Louise protocol with 0 (slept as usual) to 3 points (could not sleep at all).
Spo2, oxygen saturation.