Table 1

Study design and proportion of the 47 children in the RSV cohort and the 93 in the control cohort seen at follow-up during the study period

Age (years)
11.5, 2 and 2.5371318
Total number (RSV, controls)47, 9347, 9347, 9347, 9346, 9246, 92
% of cohort (RSV and controls)10010010010098.598.5
Questionnaire××××××
Examination××× (46, 89)× (45, 89)× (42, 87)
Skin prick tests (RSV, controls)× (47, 92)× (45, 92)× (44, 89)× (42, 87)× (41, 85)
 Egg white×××
 Cat××××
 Dog×××
 Horse×××
 Birch××××
 Timothy×××
 Mugworth××
 HDM (D pteronyssinus)××××
 HDM (D farinae)××
 Mould (Cladosporium herbarum)×××
 Mould (Alternaria alternata)××
Blood samples×× (44, 87)× (44, 86)× (41, 85)
IgE to food allergens (Fx5)××
IgE to inhaled allergens (Phadiatop)×××× (41, 85)
Blood eosinophil counts× (40, 86)
Lung function tests× (44, 86)× (44, 86)× (42, 86)
Spirometry×××
Multiple breath washout (LCI)× (41, 86)
FeNO× (42, 86)
DACh× (43, 86)× (41, 86)
  • Numbers in parentheses (RSV, controls) if differed from numbers followed up at that time point.

  • A skin prick test weal with a mean diameter ≥3 mm was regarded positive. Phadiatop (Pharmacia Upjohn Diagnostics AB, Uppsala, Sweden) is a screening test for antibodies to inhaled allergens. Fx5 (Pharmacia Upjohn Diagnostics AB, Uppsala, Sweden) is a screening test for food allergens.

  • HDM, house dust mite; DACh, dry air hyperventilation challenge; LCI, lung clearance index; FeNO, fractional exhaled nitric oxide; RSV, respiratory syncytial virus.