Table 2

Positive (PPV) and negative (NPV) predictive values (95% CIs) for serology as an indicator of P aeruginosa ≥105 colony-forming units/ml in bronchoalveolar lavage (BAL) fluid cultures

NSensitivitySpecificityPPVNPV
Multiple P aeruginosa antigens
BAL
 Discovery population760.91 (0.74 to 1.0)0.64 (0.57 to 0.72)0.14 (0.06 to 0.23)0.99 (0.97 to 1.0)
 Test population560.53 (0.28 to 0.79)0.82 (0.75 to 0.88)0.26 (0.1 to 0.41)0.94 (0.89 to 0.98)
P aeruginosa exotoxin A
BAL
 Discovery population760.82 (0.59 to 1.0)0.57 (0.485 to 0.65)0.11 (0.04 to 0.18)0.98 (0.95 to 1.0)
 Test population560.93 (0.80 to 1.0)0.52 (0.43 to 0.61)0.19 (0.10 to 0.28)0.98 (0.96 to 1.0)