Table 1

Nasal potential difference (PD) results in infants with hypertrypsinaemia (HIRT) compared with those with classic cystic fibrosis (CF) and healthy controls (Ctrl)

	CF	Ctrl	HIRT	HIRT-Nl	HIRT-CF	HIRT/Ctrl	HIRT/CF	HIRT-Nl/Ctrl	HIRT-Nl/CF	HIRT-CF/Ctrl	HIRT-CF/CF	HIRT-Nl/HIRT-CF
No. of patients	67	29	21	8	13	p Value	p Value	p Value	p Value	p Value	p Value	p Value
Age (years)	14 (7.5)	27 (11)	2 (2.1)	1.7 (2.9)	2 (1.8)	<10⁻⁴	<10⁻⁴	<10⁻⁴	<10⁻⁴	<10⁻⁴	<10⁻⁴	0.71
Maximum basal PD	−51 (16)	−15 (11)	−22.5 (14)	−17 (12)	−30 (15)	0.003	<10⁻⁴	0.42	<10⁻⁴	<10⁻⁴	<10⁻⁴	0.02
ΔAmiloride	28 (17)	6 (6.7)	9 (6.7)	6.3 (3.5)	12.2 (7)	0.03	<10⁻⁴	0.74	<10⁻⁴	0.01	<10⁻⁴	0.004
∆LowCl^–-Iso	0 (7)	−15 (11)	−6 (5.7)	−9 (4)	−3 (4)	<10⁻⁴	<10⁻⁴	0.008	<10⁻⁴	<10⁻⁴	0.0006	0.0006

Results are presented as median (IQR). Comparison with Mann–Whitney test.
Patients with HIRT-Nl have a diagnostic score >0.27, patients with HIRT-CF have a diagnostic score ≤0.27.