Statistical analysis of the case–control study
| SNPs | Controls | Cases | OR(95% CI) | p Value | Acute* | p Value | Chronic* | p Value | ||
| rs1049550 | Allele | T | 283 (45%) | 244 (35%) | 1 | 82 (35%) | 119 (34%) | |||
| C | 343 (55%) | 454 (65%) | 1.54 (1.23 to 1.92) | 0.00014 | 152 (65%) | 0.0073 | 233 (66%) | 0.0005 | ||
| Genotype | TT | 65 (21%) | 48 (14%) | 1 | 18 (16%) | 24 (14%) | ||||
| CT | 153 (49%) | 148 (42%) | 1.31 (0.85 to 2.03) | 0.2245 | 46 (39%) | 71 (40%) | ||||
| CC | 95 (30%) | 153 (44%) | 2.18 (1.39 to 3.43) | 0.00065 | 53 (45%) | 0.0143 | 81 (46%) | 0.0018 | ||
| rs2573346 | Allele | T | 303 (47%) | 260 (37%) | 1 | 86 (36%) | 129 (35%) | |||
| C | 341 (53%) | 452 (63%) | 1.55 (1.24 to 1.92) | 0.00008 | 150 (64%) | 0.0050 | 239 (65%) | 0.00074 | ||
| Genotype | TT | 71 (22%) | 50 (14%) | 1 | 18 (16%) | 26 (15%) | ||||
| CT | 161 (50%) | 160 (45%) | 1.41 (0.93 to 2.15) | 0.1097 | 50 (42%) | 77 (43%) | ||||
| CC | 90 (28%) | 146 (41%) | 2.30 (1.47 to 3.60) | 0.00022 | 50 (42%) | 0.0131 | 76 (42%) | 0.0027 |
Significant associations are shown in bold.
↵* Only patients with unequivocal classification were included.