Score performance indicators | Whole cohort (n=987) | Younger adults (n=348) | Elderly (n=438) | Very old (n=201) | |
PSI | Area under ROC curve (95% CI) | 0.83 (0.78 to 0.87) | 0.87 (0.77 to 0.97) | 0.85 (0.80 to 0.90) | 0.69 (0.60 to 0.79) |
Sensitivity, specificity under recommended cut-off point | IV (95.6%, 51.3%) | IV (88.9%, 80.6%) | IV (100%, 38.3%) | IV (100%, 19.8%) | |
Sensitivity, specificity under adjusted cut-off point | V (72.1%, 80.7%) | IV (83.3%, 82.4%) | V (83.9%, 79.6%) | V (68.4%, 59.3%) | |
PPV, NPV under recommended cut-off point | IV (21.7%, 97.5%) | IV (33.3%, 97.5%) | IV (23.9%, 98.5%) | IV (14.9%, 94.7%) | |
PPV, NPV under adjusted cut-off point | V (12.5%, 99.6%) | IV (33.3%, 97.5%) | IV (23.9%, 98.5%) | V (11.5%, 100%) | |
CURB-65 | Area under ROC curve (95% CI) | 0.73 (0.67 to 0.79) | 0.80 (0.67 to 0.93) | 0.73 (0.65 to 0.82) | 0.60 (0.48 to 0.73) |
Sensitivity, specificity under recommended cut-off point | 3 (81.9%, 48.5%) | 3 (22.2%, 99.7%) | 3 (64.5%, 74.7%) | 3 (47.4%, 65.9%) | |
Sensitivity, specificity under adjusted cut-off point | 2 (83.8%, 52.3%) | 2 (61.1%, 95.8%) | 3 (64.5%, 74.7%) | 3 (47.4%, 65.9%) | |
PPV, NPV under recommended cut-off point | 3 (16.6%, 95.6%) | 3 (80.0%, 95.9%) | 3 (16.3%, 96.5%) | 3 (12.7%, 92.3%) | |
PPV, NPV under adjusted cut-off point | 2 (11.5%, 97.8%) | 2 (44.0%, 97.8%) | 3 (16.3%, 96.5%) | 3 (12.7%, 92.3%) |
NPV, negative predictive value; PPV, positive predictive value.