Binary logistic regression analysis to assess the association between presence or absence of COPD and the rs7041 genetic variant (under a recessive model of inheritance) (n=403)
| Risk of COPD | ||||
| Model without 25-OHD | Model with 25-OHD | |||
| OR (CI) | p Value | OR (CI) | p Value | |
| 25-OHD | 0.94 (0.91 to 0.96) | <0.0001 | ||
| Age | 1.10 (1.06 to 1.13) | <0.0001 | 1.09 (1.06 to 1.14) | <0.0001 |
| Pack-years | 1.02 (1.01 to 1.03) | 0.003 | 1.01 (1.00 to 1.02) | 0.05 |
| rs7041 | 2.11 (1.20 to 3.71) | 0.009 | – | – |
| Quit-years | – | – | – | – |
| Gender | – | – | – | – |
A model without 25-OHD (ng/ml) as an explanatory variable is compared with a model in which 25-OHD was included. Non-significant covariates quit-years, gender and rs7041 (in the model with 25-OHD) are listed in the table but not included in the final represented model.
COPD, chronic obstructive pulmonary disease; 25-OHD, 25-hydroxyvitamin D.