Patient characteristics
| Patients with COPD (n=12) | Control subjects (n=7) | p Value | |
| Male/female | 8/4 | 2/5 | 0.1698 |
| Age (years) | 60±7 | 60±11 | 0.9977 |
| Weight (kg) | 70±22 | 71±12 | 0.9245 |
| BMI (kg/m2) | 25±6 | 27±3 | 0.4466 |
| FEV1 (l) | 1.42±0.70 | 2.42±0.80 | 0.0072 |
| FEV1 (% predicted) | 50±17 | 103±6 | <0.0001 |
| FEV1/FVC (%) | 53±14 | 74±2 | 0.0002 |
| ITGV (% predicted) | 118±17 | 111±5 | 0.1750 |
| RV (% predicted) | 172±44 | 109±18 | 0.0008 |
| RV/TLC (%) | 52±11 | 37±6 | 0.0087 |
| Tlco (% predicted) | 75±20 | 101±22 | 0.0325 |
| Pao2 (mm Hg) | 69.8±10.7 | – | – |
| Paco2 (mm Hg) | 39.9±0.3 | – | – |
| Albumin (g/l) | 43±3 | 43±1 | 0.5773 |
| Final diagnosis | |||
| Non-small cell lung carcinoma | |||
| Stage Ia | 0 | 3 | |
| Stage Ib | 5 | 1 | |
| Stage IIIa | 0 | 1 | |
| Stage IIIb | 1 | 0 | |
| Non-pulmonary cancer | 0 | 1 | |
| Bullous emphysema | 4 | 0 | |
| Subapical blebs | 0 | 1 | |
| Benign pulmonary nodule | 2 | 0 | |
BMI, body mass index; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; ITGV, intrathoracic gas volume; Paco2, Pao2, arterial carbon dioxide and oxygen tensions; RV, residual volume; TLC, total lung capacity; Tlco, transfer factor.