Median change from baseline to months 3 and 27 for spirometry parameters (combined 28-day and 56-day TIS groups)
| Month 3 | Month 27 | |
| FEV1 % predicted | 0.6 (n=39) | –1.3 (n=18) |
| FVC % predicted | –2.7 (n=39) | –2.3 (n=18) |
| FEF25–75 % predicted | –0.1 (n=36) | 0.2 (n=17) |
FEF25–75, forced expiratory flow between 25% and 75%; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; TIS, tobramycin inhalation solution.