Association between infection with Mycobacterium tuberculosis and risk factors for the 168 children in the outbreak population
| Infected (%) | ||||||||
| Not infected (%) | Latent | Active | Not infected (%) | Univariate OR (95% CI) | Multivariable OR (95% CI) | p Value (multivariable analysis) | ||
| BCG vaccinated | Yes (n=53) | 46 (87) | 6 (11) | 1 (2) | 0 | 0.28 (0.11 to 0.70) | 0.25 (0.09 to 0.69) | 0.008 |
| No (n=73) | 47 (64) | 19 (26) | 7 (10) | 0 | * | * | * | |
| NK (n=42) | 21 (50) | 5 (12) | 1 (2) | 15 (36) | ||||
| Age group | 0–2 years (n=77) | 58 (75) | 9 (12) | 4 (5) | 6 (8) | * | * | * |
| 3–4 years (n=77) | 49 (64) | 20 (26) | 5 (6) | 3 (4) | 2.28 (1.05 to 4.92) | 0.36 (0.11 to 1.21) | 0.098 | |
| 5–9 years (n=4) | 3 (75) | 1 (25) | 0 | 0 | 1.49 (0.14 to 15.47) | 0.89 (0.03 to 23.98) | 0.946 | |
| NK (n=10) | 4 (40) | 0 | 0 | 6 (60) | ||||
| Sex | Male (n=91) | 62 (68) | 15 (17) | 3 (3) | 11 (12) | * | * | * |
| Female (n=77) | 52 (68) | 15 (19) | 6 (8) | 4 (5) | 1.39 (0.67 to 2.89) | 1.85 (0.71 to 4.78) | 0.207 | |
| Index contact | Yes (n=86) | 49 (57) | 28 (33) | 7 (8) | 2 (2) | 11.61 (3.87 to 34.83) | 18.91 (4.43 to 80.79) | <0.001 |
| No (n=82) | 65 (79) | 2 (2.5) | 2 (2.5) | 13 (16) | * | * | * | |
Univariable ORs relate the odds of being an infected contact (as defined by IGRA positivity) for each risk factor. IGRA results are available for 153/168 children. The multivariate ORs are adjusted for all variables shown in the table and include the 123 children for which information was available for all the variables.
↵* Referent.NK, not known.