NICE protocol (CXR first), 280 immigrants | |||
Step1: CXR if age >11 and not pregnant | |||
Unit cost | Total cost | ||
275 CXR | £23.24 | £6393.75 | |
Step 2: TST if pregnant or age <16 (12 individuals) or age 16–35 from sub-Saharan Africa or from country with TB incidence >500/105 (209 individuals) | |||
221 TST | £13.69 | £3025.49 | |
Step 3: QFT if positive TST (estimated TST-positive rate 69%) | |||
153 QFT | £25.67 | £3927.51 | |
Total cost for screening | £13 346.75 | ||
LTBI cases (estimated QFT-positive rate 54%) | 83 | ||
Cost per case LTBI identified | £160.81 |
CXR, chest x ray; LTBI, latent tuberculosis infection; NICE, National Institute for Health and Clinical Excellence; QFT, QuantiFERON-TB Gold; TST, tuberculin skin test.