Association between maternal smoking during and after pregnancy and children’s lung function at 21 years (males only)
| Maternal smoking | Lung function tests | |||||
| FVC (litre) | FEV1 (litre) | FEF25–75 (litre/s) | ||||
| Univariate | Multivariate | Univariate | Multivariate | Univariate | Multivariate | |
| First clinic visit | −0.003 (0.05) | −0.155 (0.09) | −0.062 (0.04) | −0.153 (0.08)** | −0.188 (0.07)* | −0.262 (0.13)** |
| 6 months | 0.026 (0.05) | 0.157 (0.10) | −0.029 (0.04) | 0.063 (0.08) | −0.144 (0.07)** | −0.071 (0.13) |
| 5 years | 0.011 (0.05) | 0.005 (0.09) | −0.009 (0.04) | 0.078 (0.07) | −0.042 (0.07) | 0.269 (0.12) |
| 14 years | 0.008 (0.05) | −0.022 (0.08) | −0.043 (0.04) | −0.054 (0.06) | −0.144 (0.07)** | −0.125 (0.11) |
Values are regression coefficients (SE).
FVC, forced vital capacity; FEF25–75, forced expiratory flow between 25% and 75%; FEV1, forced expiratory volume in 1 s
*p<0.01; **p<0.05.