Table 1

Pooled performance characteristics of severity scores for predicting mortality in community-acquired pneumonia

SensitivitySpecificityPLRNLRDORAUROC
PSI
 ≥III98.2% (97.8–98.5%)38.8% (38.4–39.2%)1.4 (1.3 to 1.6)0.08 (0.06 to 0.12)18.1 (11.5 to 28.5)0.88 (0.02)
 ≥IV91.4% (90.8–92.1%)49.5% (49.2–49.9%)1.9 (1.8 to 2.0)0.2 (0.17 to 0.24)9.6 (8.0 to 11.6)0.82 (0.01)
 ≥V63.2% (62.1–64.3%)83.6% (83.4–83.9%)4.1 (3.7 to 4.5)0.5 (0.44 to 0.58)8.4 (7.2 to 9.8)0.81 (0.01)
CURB65
 ≥198.6% (97.6–99.2%)26.5% (26.5–27.4%)1.2 (1.1 to 1.3)0.10 (0.06 to 0.16)13.6 (9.3 to 22.3)0.86 (0.02)
 ≥289.1% (87.1–90.8)52.2% (51.3–53.1%)1.7 (1.5 to 1.9)0.21 (0.15 to 0.30)8.3 (5.8 to 11.9)0.81 (0.02)
 ≥362.0% (59.3–64.6%)80.8% (80.2–81.4%)3.1 (2.7 to 3.5)0.46 (0.40 to 0.54)7.0 (5.8 to 8.3)0.79 (0.01)
 ≥429.0% (26.3–31.8%)95.3% (95.0–95.7%)5.4 (4.4 to 6.6)0.73 (0.65 to 0.83)7.8 (6.3 to 9.6)0.80 (0.01)
CRB65
 ≥194.4% (94.2–94.6%)38.3% (38.1–38.5%)1.3 (1.2 to 1.5)0.15 (0.10 to 0.22)9.4 (5.8 to 15.3)0.82 (0.03)
 ≥272.7% (69.3–76.0%)70.8% (69.8–71.8%)2.4 (1.9 to 3.0)0.39 (0.28 to 0.54)6.3 (4.4 to 9.2)0.78 (0.02)
 ≥329.1% (28.8–29.5%)90.9% (90.8–91.0%)4.4 (3.6 to 5.5)0.72 (0.66 to 0.79)6.9 (4.9 to 9.5)0.79 (0.02)
  • AUROC, area under the receiver operator characteristic curve; DOR, diagnostic OR; NLR, negative likelihood ratio; PLR, positive likelihood ratio; PSI, Pneumonai Severity Index.